The mice are maintained in a conventional facility using
a static caging system. Rodents are permitted entry into the
facility after an 8 week quarantine period. The health status
of all the colonies are monitored monthly by exposing sentinel
cages containing Tac: (SW)fBR female mice to solied bedding.
Each holding room contains at least 2 sentinel cages (1 sentinel
per 200 resident cages). One mouse per sentinel cage is evaluated
during each testing cycles as indicated below:
There are three separate testing cycles: quarterly; semiannual;
and annual. The agents screened at each interval are as follows:
| Every Other Month |
Semiannual |
Annual |
| |
Every other month testing including: |
Semiannual testing including: |
SEND
|
LCMV |
MTLV |
PVM
|
MAV |
MCMV |
| MHV |
ECTRO |
Hantaan |
| MVM |
K |
E. cuniculi |
| MPV-1 |
POLY |
CAR bacillus |
| MPV-2 |
Cecal/duodenal exam for protozoa |
|
| NS-1 |
Rectal culture for Salmonella sp. and C. rodentium (pooled) |
|
| GDVII |
Aerobic respiratory tract culture (pooled) |
|
| REO |
Exam for cecal and colon for helminthes |
|
| EDIM |
Exam of colon for Helicobacter sp.,
H.hepaticus and H.bilis |
|
| MPUL |
Gross pathology; histology if needed |
|
| MNV |
Fecal Exam for Helicobacter sp., H. hepaticus and H.bilis |
|
| Pooled Fecal Float |
|
|
| Anal Tape Test |
|
|
| Helicobacter Testing as needed |
|
|
